What cells are responsible for the c-wave in an ERG?

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Multiple Choice

What cells are responsible for the c-wave in an ERG?

Explanation:
The c-wave is driven by outer-retina cells that respond to how ions (especially potassium) move in the subretinal space after photoreceptor activity. It mainly reflects the activity of the retinal pigment epithelium (RPE) and Müller glial cells rather than the photoreceptors or bipolar cells themselves. When photoreceptors change state with light, potassium builds up outside them; Müller cells buffer this K+ and communicate with the RPE, which uses ion pumps and channels to restore balance. The coordinated response of these glial/RPE cells produces the slow, positive deflection seen as the c-wave. So the cells responsible are glial cells in the retina and the RPE.

The c-wave is driven by outer-retina cells that respond to how ions (especially potassium) move in the subretinal space after photoreceptor activity. It mainly reflects the activity of the retinal pigment epithelium (RPE) and Müller glial cells rather than the photoreceptors or bipolar cells themselves. When photoreceptors change state with light, potassium builds up outside them; Müller cells buffer this K+ and communicate with the RPE, which uses ion pumps and channels to restore balance. The coordinated response of these glial/RPE cells produces the slow, positive deflection seen as the c-wave. So the cells responsible are glial cells in the retina and the RPE.

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